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For more than 30 indications, including breast, genitourinary, colorectal, blood and lung cancers, as well as melanoma. This extension does not include potential pediatric exclusivity. Today, we have an industry-leading portfolio of 24 approved innovative cancer medicines and vaccines.

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IBRANCE when taken in combination with an aromatase inhibitor as initial endocrine based therapy in postmenopausal women or in men; or with fulvestrant in patients requiring hemodialysis. The dose of sensitive CYP3A substrates with a narrow therapeutic index may need to be reduced as IBRANCE may increase their exposure. One death due to neutropenic sepsis was observed in PALOMA-3.

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